Drug Delivery

SUNBRIGHT® DSPE-020DB (DSPE-PEG-DBCO)

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SUNBRIGHT DSPE-020DB is a functionalized PEG phospholipid designed to enhance the performance of lipid nanoparticle (LNP) and liposomal formulations in active targeting delivery systems. It features a DBCO group linked to a PEG phospholipid (DSPE-PEG2000), providing a versatile platform for bioconjugation. The DBCO group site-specifically reacts with azide groups introduced on bioactive molecules such as peptides, antibodies, or other ligands via click chemistry, enabling the creation of LNPs with enhanced precise cellular targeting.

DSPE-PEG-DBCO


Alkyl Composition R1COO= C18:0, R2COO= C18:0
Applications LNP, Liposome and Lipid Complex
Chemical Name N-[(4-dibenzoazacyclooctyl-1,4-dioxobutyl) aminopropylpolyoxyethylene oxycarbonyl]-1,2-distearoyl-sn-glycero-3-phosphoethanolamine, sodium salt
Functional Groups DBCO
MW 2,000
Package Size 100mg, 1g
Product categories Activated PEG Phospholipids
Target Groups Azide