Drug Delivery

SUNBRIGHT® DSPE-020CN (DSPE-PEG)

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SUNBRIGHT DSPE-020CN (DSPE-PEG2000) can be applied to lipid nanoparticle (LNP) and liposomal formulations to extend the half-life in the bloodstream. Coating of the surface of LNPs or liposomes with polyethylene glycol (PEG) suppresses drug clearance in vivo by the reticuloendothelial system, thereby prolonging the half-life of the drug. DSPE-020CN has a carbamate linkage that is resistant to hydrolysis between the PEG moiety and DSPE (distearoyl phosphatidylethanolamine), and therefore is used for commercial production of PEGylated liposomes. DSPE-020CN can also be used as emulsifiers and stabilizers of microspheres in aqueous solutions.


Acronym DSPE-PEG 2,000
Alkyl Composition R1COO= C18:0, R2COO= C18:0
Applications LNP, Liposome and Lipid Complex
CAS Registry Number 247925-28-6
Chemical Name N-(Methylpolyoxyethylene oxycarbonyl)-1,2-distearoyl-sn-glycero-3-phosphoethanolamine, sodium salt
Drug Master File Registered (DMF#: 019731)
MW 2,000
Package Size 1g, 10g
Product categories PEG Phospholipids
Package size
$198.00
$198.00
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