PUREBRIGHT® MA-P12-PS

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PUREBRIGHT MA-P12-PS is a pendant-type heterobifunctional monodisperse PEG linker, featuring two monodisperse PEG chains and two different functional groups—a maleimide and an NHS carbonate.

This unique pendant-like structure forms a hydrophilic domain surrounding hydrophobic payloads, effectively masking their hydrophobicity and improving aqueous solubility. It also allows the drug to be positioned closer to the antibody while reducing nonspecific interactions.

MA-P12-PS is particularly suited for antibody-drug conjugate (ADC) linker design, where precise control over linker length, hydrophilicity, and dual functional reactivity is critical.

Pendant EG12,
Maleimide-Propionic acid NHS ester

Applications ADC and Linker

Functional Groups Maleimide, NHS ester

MW 1,640.81

Package Size 100mg

PEG Type Monodisperse PEG

Target Groups Amine, Hydroxyl, Thiol

Package size

100mg amber glass bottle

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