CHINPI EXTRACT PM-F(N)™
CHINPI EXTRACT PM‑F™ is a citrus-derived extract enriched with polymethoxyflavones (PMFs), including heptamethoxyflavone, nobiletin, and tangeretin. These components are characteristic flavonoids of citrus fruits and are present at approximately 1% within the extract. The extract is designed as a skin‑brightening ingredient based on its activity in cell-based evaluations.
Structure
- INCI: CITRUS AURANTIUM DULCIS (ORANGE) PEEL EXTRACT, WATER, BUTYLENE GLYCOL
- Chinese INCI: 甜橙 (CITRUS AURANTIUM DULCIS) 果皮提取物, 水, 丁二醇
Features
- Contains approximately 1% PMFs, including heptamethoxyflavone, nobiletin, and tangeretin
- Demonstrates inhibitory effects on melanin production in cultured human melanoma cells at low concentrations
- Shows reduced tyrosinase activity and decreased tyrosinase protein expression based on western blot and cell assays
- Exhibits suppression of COX‑2 expression and UV‑induced PGE₂ production
- Confirmed skin‑whitening effect in a clinical evaluation using a 1% cream formulation
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