[High-Purity mPEG-OH: Starting Material for Activated PEGs]
NOF manufactures high-purity methoxy-PEG-OH characterized by the absence of contaminating impurities and narrow molecular weight distributions. These highly pure methoxy-PEG-OH have so far been used for various commercial PEGylated drugs, such as PEG-Interferon and PEG-GCSF.
CH3O(CH2CH2O)n-H
NOF CORPORATION is the sole worldwide patent holder of these high-purity mPEG-OH and all their derivatives. *Patent No.: JP3050228, US6455639, KR0358276
Our methoxy-PEG-OH has the advantage of extremely low diol contents relative to those of competitors' products. As shown in the following graphs, our methoxy-PEG-5000 contains remarkably low levels of diol as impurities, besides providing a narrower distribution of molecular weights in comparison with our competitors' products. Employment of our methoxy-PEG-OH as the starting materials yields higher purity and higher activity of Activated PEGs. We manufacture highly our methoxy-PEGs with molecular weights from 2kDa to 80kDa.
