MPC-based surface modifier
The Lipidure®-CR3001 is a surface modifier for metals and silicone rubber that can provide excellent hydrophilicity and excellent biocompatibility.
Hydrophilization of Silicone Rubber Surface
A silicone rubber sheet was modified with Lipidure®-CR3001. Contact angle (air in water) of the CR3001-modified surface was measured to confirm the improvement of hydrophilicity.
Lipidure®-CR3001 impart excellent
hydrophilicity to silicone rubber surface.
Coating Procedure
Mechanism of Immobilizing Lipidure®-CR3001
MPC : A Source of Ultra High Hydrophilicity
MPC is a methacrylic monomer having phosphoryl choline group.
✓ Phosphoryl choline is a hydrophilic part of phospholipid, which
exists on cell membrane.
✓ Phosphoryl choline coating imparts excellent biocompatibility
and excellent hydrophilicity onto the substrate.
Above Img: 2-Methacryloyloxyethyl Phosphoryl Choline
Alkoxy silane: A crosslinking point
- Alkoxy silane group is hydrolyzed in an acidic condition to form silanol group [-Si(OH)3].
- In coating process, hydrogen bond is formed between the silanol and hydroxy group on the substrate.
- Dehydration condensation occurs in heating process to form Si-O covalent bond.
