MPC Polymer, BIOLIPIDURE®, for diagnostic assays
BIOLIPIDURE® is a series of MPC-based polymers that is useful for designing In Vitro Diagnostics (IVD) and biochemical assay reagent.
BIOLIPIDURE® exhibits multiple functions, such as suppression of non-specific adsorption of protein, stabilization of protein, sensitization in immunoassays, and so on. As BIOLIPIDURE® is fully synthetic materials, the products are provided with high stability (at least 1 year in a cold storage), little lot-to-lot variation, and little biohazardous risk. With these features, BIOLIPIDURE® is superior to protein-based reagents, namely bovine serum albumin (BSA), casein, etc.
BIOLIPIDURE® is provided as 5 wt% aqueous solution (5% polymer and 95% water) with no preservatives or other subspecies.
| Subseries | Product name | Feature |
|---|---|---|
| 100 | BIOLIPIDURE®-103 | Very hydrophilic |
| 200 | BIOLIPIDURE®-203, 204, 205, 206 | Moderately or relatively hydrophobic |
| 400 | BIOLIPIDURE®-401, 402, 403, 405, 406, 407 | Very hydrophilic (Anionic) |
| 500 | BIOLIPIDURE®-502, 504 | Very hydrophilic (Cationic) |
| 700 | BIOLIPIDURE®-702 | H-bond acceptor |
| 800 | BIOLIPIDURE®-802, 803, 804 | Relatively hydrophobic |
| 1000 | BIOLIPIDURE®-1002, 1003 | Moderately hydrophobic |
| 1200 | BIOLIPIDURE®-1201 | Moderately hydrophobic |
| 1300 | BIOLIPIDURE®-1301 | Moderately hydrophobic |
| 1700 | BIOLIPIDURE®-1701 | Reactive group (NH₂・HCl) |
| Assay | Blocking | Stabilizing | Sensitizing |
|---|---|---|---|
| Latex agglutination | 200, 800, 1200 | 800 | 100, 400 |
| ELISA/CLEIA (microplate) | 200, 800, 1000, 1200 | 200, 800 | - |
| CLEIA (magnetic beads) | 200, 1000 | 800 | - |
| Lateral flow (with latex) | 200, 800 | 800 | 100 |
| Lateral flow (with gold nano-particle) | 200, 800 | 800 | 400 |
