For site specific delivery, lipid nanoparticles (LNPs) modified with ligands are widely used. SUNBRIGHT GS-020MA is a functionalized PEG lipid designed for efficient ligand conjugation in LNP drug delivery systems. It features a maleimide group linked to a PEG diacylglycerol (DSG-PEG2000), which allows site-specific conjugation with thiol-containing molecules such as peptides, antibodies, or other ligands, and enables precise cellular targeting and enhanced formulation versatility of LNPs. GS-020MA does not have a charge that could adversely affect the stability of LNPs and is useful for developing active targeting delivery systems.
Chemical Name: 1,2-Distearoyl-rac-glycero-3-(2’-maleimidoethyl)polyoxyethylene
CAS#:
PEG chain Molecular weight: 2000
RCOO= C18:0
Package size: 100mg or 1g