6. Degradable PEGs
NOF has developed novel degradable PEGs that have enzyme cleavable peptide linkers.
Degradable PEGs have the same blood circulation time as non-degradable PEGs and are removed from the body faster than non-degradable PEGs because they are cleaved to lower molecular weight PEG in cells.

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Degradable PEGs in cells were completely degraded by intracellular enzymes.
Additionally, degradable PEGs were stable in the serum as same as non-degradable PEGs.







