UltraPure Polysorbate 80
Polysorbate80(HX2)™
Polyoxyethylene Sorbitan Oleate
Polysorbate80(HX2)™ produced by NOF CORPORATION is an ultrapure product of the highest quality in the world, with extremely low aldehyde and peroxide levels.
These characteristics contribute to its safety; in a rat study, Polysorbate 80 (HX2)™, as compared to conventional Polysorbate 80 formulations, triggered less histamine release from mast cells. In vitro dog study has also indicated less histamine release with our Polysorbate 80 (HX2) TM; as a natural consequence, because of the lower incidence of allergy noted, our Polysorbate 80 (HX2)™ has drawn worldwide attention.
Influence on Basophillic leukocyte
Basophilic leukocytes were immersed in 1% Polysorbate 80 solution for 30 min. The cells were immobilized in glutaraldehyde and observed by SEM.
Status of Chinese Pharmacopoeia (ChP)