Phospholipids and Lipids for LNP and Liposome
COATSOME® Series
Using the latest synthetic and purification technologies, NOF manufactures and supplies highly purified lipids derivatives (COATSOME® Series) suitable for lipid emulsion formulations, liposome formulations and lipid nanoparticle formulations which are extensively used for pharmaceuticals. Various kinds and grades of phospholipids are readily available. In addition, we can respond to requests from our customers with the tailor-made synthesis of any phospholipids with the desired structures.
We also offer novel lipid derivatives, especially for nucleic acid delivery.
When PEGylated lipids are used as liposomes or lipid nanoparticles, the aqueous corona at the liposome surface facilitates stable dispersion in aqueous solutions and increases stability in vivo.
[cGMP Manufacturing Facility]
Bulk phospholipids produced at our own validated facility under cGMP operation have been supplied worldwide for commercial drugs with long-standing reputations for quality and reliability for many years.
[Drug Master Filings]
NOF has already submitted more than 35 DMFs regarding various kinds of NOF manufactured phospholipids to the US FDA, so that customers can rely on our quality. We submit DMFs according to customers' requests and development needs.
[Custom Synthesis]
Custom synthetic phospholipids and lipids can be produced at customers' request.
For Gene and Nucleic Acid Delivery
