DOTAP is a widely used cationic lipid enabling efficient delivery of nucleic acids and therapeutic agents in lipid-based formulations. Its positive charge promotes electrostatic interactions with negatively charged DNA and RNA, forming stable nanoparticles that enhance cellular uptake and gene transfection efficiency.
Acronym: DOTAP (powder or solid form)
Chemical Name: 1,2-Dioleoyloxy-3-trimethylammonium propane chloride
CAS#: 132172-61-3
Molecular weight: 698.5
Alkyl composition: R1COO= C18:1, R2COO= C18:1
Package size: 1g