{"product_id":"sunbright-me-3e200fh-ea","title":"SUNBRIGHT® ME-3E200FH-EA","description":"\u003cp\u003eSUNBRIGHT ME-3E200FH-EA is a pH-triggered releasable PEG derivative incorporating an acid-cleavable acetal linker, designed to release conjugated pharmaceutical substances under mildly acidic conditions (pH 4–6), such as in endosomes, lysosomes, or tumor tissues. It consists of a 20 kDa PEG chain connected to an acid-cleavable linker that has a primary amine group as a functional group.\u003c\/p\u003e\u003cp\u003eThe acetal linker remains stable at physiological pH (7.4) while selectively cleaving under acidic environments to trigger drug release. The release rate can be fine-tuned by modifying the substituents on the benzene ring.\u003c\/p\u003e\u003cp\u003eME-3E200FH-EA offers excellent serum stability and storage stability, making it particularly suitable for targeted drug delivery systems requiring precise control of release timing in specific biological environments.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e","brand":"NOF AMERICA","offers":[{"title":"100mg amber glass bottle","offer_id":42782109990996,"sku":"161G981SE103KK100F","price":198.0,"currency_code":"USD","in_stock":false},{"title":"1g amber glass bottle","offer_id":42782110023764,"sku":"161G981SE101KK1G","price":990.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0643\/8292\/6932\/files\/ME-3E050FH-EA.jpg?v=1766525206","url":"https:\/\/nofamerica.com\/products\/sunbright-me-3e200fh-ea","provider":"NOF AMERICA CORPORATION","version":"1.0","type":"link"}