{"product_id":"sunbright-me-3e050fh-ts","title":"SUNBRIGHT® ME-3E050FH-TS","description":"\u003cp\u003eSUNBRIGHT ME-3E050FH-TS is a pH-triggered releasable PEG derivative incorporating an acid-cleavable acetal linker, designed to release conjugated pharmaceutical substances under mildly acidic conditions (pH 4–6), such as in endosomes, lysosomes, or tumor tissues. It consists of a 5,000 Da PEG chain connected to an acid-cleavable linker that has an NHS carbonate group as a functional group.\u003c\/p\u003e\u003cp\u003eThe acetal linker remains stable at physiological pH (7.4) while selectively cleaving under acidic environments to trigger drug release. The release rate can be fine-tuned by modifying the substituents on the benzene ring.\u003c\/p\u003e\u003cp\u003eME-3E050FH-TS offers excellent serum stability and storage stability, making it particularly suitable for targeted drug delivery systems requiring precise control of release timing in specific biological environments.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e","brand":"NOF AMERICA","offers":[{"title":"100mg amber glass bottle","offer_id":42782130012244,"sku":"161G981ST003KK100F","price":297.0,"currency_code":"USD","in_stock":false},{"title":"1g amber glass bottle","offer_id":42782130045012,"sku":"161G981ST001KK1G","price":990.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0643\/8292\/6932\/files\/ME-3E200FH-TS.jpg?v=1766525303","url":"https:\/\/nofamerica.com\/products\/sunbright-me-3e050fh-ts","provider":"NOF AMERICA CORPORATION","version":"1.0","type":"link"}