{"product_id":"sunbright-me-3c200bd-np","title":"SUNBRIGHT® ME-3C200BD-NP","description":"\u003cp\u003eSUNBRIGHT ME-3C200BD-NP is a novel acetal linkage releasable PEG with a self-immolative linker structure, designed to release native bioactive substances under physiological conditions. It consists of a 20 kDa PEG chain conjugated to a cleavable aromatic acetal unit, enabling gradual release through hydrolysis.\u003c\/p\u003e\n\u003cp\u003eThe release rate of the bioactive substance can be finely tuned by modifying the substituent on the aromatic ring. In vitro studies demonstrated that ME-3C200BD-NP exhibited a half-life of approximately 7.5 days at pH 7.4, allowing controlled release kinetics suitable for protein and peptide conjugation.\u003c\/p\u003e\n\u003cp\u003eME-3C200BD-NP is a useful material for advanced drug delivery, enhancing the blood stability of bioactive substances and achieving prolonged bioactivity by gradually releasing the native bioactive substance into the bloodstream.\u003c\/p\u003e\n\u003cp\u003ea-{2-methyl-4-[6-methyl-8-({[(4-nitrophenoxy)carbonyl]oxy}methyl)-4H-benzo[d][1,3]dioxin-2-yl]phenyl}-w-methoxy, poly(oxyethylene)\u003c\/p\u003e\n\u003cp\u003eIn vitro half-life (pH7.4) 7.5d\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"NOF AMERICA","offers":[{"title":"100mg amber glass bottle","offer_id":42782109630548,"sku":null,"price":165.0,"currency_code":"USD","in_stock":false},{"title":"1g amber glass bottle","offer_id":42782109663316,"sku":null,"price":770.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0643\/8292\/6932\/files\/ME-3C200BD-NP.jpg?v=1766524097","url":"https:\/\/nofamerica.com\/products\/sunbright-me-3c200bd-np","provider":"NOF AMERICA CORPORATION","version":"1.0","type":"link"}