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CyPA®-PW, CyPA®-ET

  CyPA®-PW, CyPA®-ET                                    
    Cyclic Phosphatidic Acid (CyPA®)                                                                         

 

 1   Characteristic                                                                                                     

 Cyclic phosphatidic acid (CyPA®) was isolated from the culture medium of slime mold (Physarum polycephalum) as the novel lysophospholipid with quite unique structure by Prof. Murofushi in 1985 (1). Later, it was also found in body fluid like serum and tear (2). Recently, we found various functions of CyPA® positive for skin treatment.
We licensed in its enzymatic process of manufacturing from Prof. Murofushi, and started providing CyPA®. We are now expanding its applications for cosmetics.

 Functions
・Increase hyaluronan production.
・Increase cytoskeleton (F-actin) and focal adhesion.
・Contract dermal model (collagen gel).
・Increase expression of transglutaminase.
・Increase expression of aquaporin 3.
・Increase water content of skin.
・Improve skin elasticity and wrinkles.
・Reduce hair follicle.

CyPA® is registered trademark of NOF CORPORATION.

      Composition                                                                                                     

 CyPA®-PW

INCI Names Content

CYCLIC LYSOPHOSPHATIDIC ACID

50.0%
CYCLODEXTRIN  50.0%

 

 CyPA®-ET 

INCI Names Content

CYCLIC LYSOPHOSPHATIDIC ACID

20.0%
WATER  40.0%
ALCOHOL 40.0%

 

 

 3  Experimental Data